FITC標(biāo)記的BH3結(jié)構(gòu)域凋亡誘導(dǎo)蛋白抗體

Name: FITC標(biāo)記的BH3結(jié)構(gòu)域凋亡誘導(dǎo)蛋白抗體bs-1153R-FITC
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簡(jiǎn)要描述：Bid, a BH3 domain containing proapoptotic Bcl2 family member, is localized in the cytosolic fraction of cells as an inactive precursor. Its active form is generated upon proteolytic cleavage by caspase 8 in the Fas signaling pathway. Cleaved Bid translocates to mitochondria and releases its potent proapoptotic activity, which in turn induces cytochrome c release and mitochondrial damage. The cytochrome c releasing activity of Bid was antagonized by Bcl2. Mutation in the SH3 domain can diminis